This item contains entries about prominent people (primarily accounts of their deaths); Philadelphia events and gossip; the Pennsylvania Hospital; questions for Meriwether Lewis on Indian physical history, medicine, morals, and religion; and his views on marriage, religion, physicians, etc. Also includes meeting with Captain Wells and Little Turtle; speculations on Indian skin color at the equator.

These photostats of letters were collected from various repositories by Lyman H. Butterfield for his book, "Letters of Benjamin Rush" 2 v. American Philosophical Society Memoirs 30(1951). Some of the topics discussed are Philadelphia and United States politics, slavery, Afro-American churches, and medicine.